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Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations
Prostasin or human channel-activating protease 1 has been reported to play a critical role in the regulation of extracellular sodium ion transport via its activation of the epithelial cell sodium channel. Here, the structure of the extracellular portion of the membrane associated serine protease has...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771310/ https://ncbi.nlm.nih.gov/pubmed/19388054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.118 |
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