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Rational redesign of neutral endopeptidase binding to merlin and moesin proteins
Neutral endopeptidase (NEP) is a 90- to 110-kDa cell-surface peptidase that is normally expressed by numerous tissues but whose expression is lost or reduced in a variety of malignancies. The anti-tumorigenic function of NEP is mediated not only by its catalytic activity but also through direct prot...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771306/ https://ncbi.nlm.nih.gov/pubmed/19388049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.114 |
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