Neuregulin 1 Transgenic Mice Display Reduced Mismatch Negativity, Contextual Fear Conditioning and Social Interactions

INTRODUCTION: Neuregulin-1 (NRG1) is one of susceptibility genes for schizophrenia and plays critical roles in glutamatergic, dopaminergic and GABAergic signaling. Using mutant mice heterozygous for Nrg1 (Nrg1(+/−)) we studied the effects of Nrg1 signaling on behavioral and electrophysiological meas...

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Main Authors: Ehrlichman, Richard S., Luminais, Steven N., White, Samantha L., Rudnick, Noam D., Ma, Nan, Dow, Holly C., Kreibich, Arati S., Abel, Ted, Brodkin, Edward S., Hahn, Chang-Gyu, Siegel, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771287/
https://ncbi.nlm.nih.gov/pubmed/19643092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.07.065
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