Development of Fibrosis in Nonalcoholic Steatosis through Combination of a Synthetic Diet Rich in Disaccharide and Low-Dose Lipopolysaccharides in the Livers of Zucker (fa/fa) Rats

Nonalcoholic steatohepatitis (NASH) can develop into end-stage disease such as cryptogenic cirrhosis and hepatocellular carcinoma. Hence, it is important to understand the pathogenesis of NASH. In general, the “two-hit theory” has prevailed as a pathogenic mechanism of NASH. According to this theory...

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Autors principals: Fukunishi, Shinya, Nishio, Hajime, Fukuda, Akira, Takeshita, Atsushi, Hanafusa, Toshiaki, Higuchi, Kazuhide, Suzuki, Koichi
Format: Artigo
Idioma:Inglês
Publicat: the Society for Free Radical Research Japan 2009
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771254/
https://ncbi.nlm.nih.gov/pubmed/19902023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.09-50
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