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Overexpression of DPAGT1 leads to aberrant N-glycosylation of E-cadherin and cellular discohesion in oral cancer

Cancer cells are frequently characterized by aberrant increases in protein N-glycosylation and by disruption of E-cadherin-mediated adherens junctions (AJs). The relationship between altered N-glycosylation and loss of E-cadherin adhesion in cancer, however, remains unclear. Previously, we reported...

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Detalhes bibliográficos
Main Authors: Nita-Lazar, Mihai, Noonan, Vikki, Rebustini, Ivan, Walker, Janice, Menko, A. Sue, Kukuruzinska, Maria A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771190/
https://ncbi.nlm.nih.gov/pubmed/19549906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4512
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