Altered endochondral bone development in matrix metalloproteinase 13-deficient mice

The assembly and degradation of extracellular matrix (ECM) molecules are crucial processes during bone development. In this study, we show that ECM remodeling is a critical rate-limiting step in endochondral bone formation. Matrix metalloproteinase (MMP) 13 (collagenase 3) is poised to play a crucia...

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Bibliografische gegevens
Hoofdauteurs: Stickens, Dominique, Behonick, Danielle J., Ortega, Nathalie, Heyer, Babette, Hartenstein, Bettina, Yu, Ying, Fosang, Amanda J., Schorpp-Kistner, Marina, Angel, Peter, Werb, Zena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771178/
https://ncbi.nlm.nih.gov/pubmed/15539485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.01461
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