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Characterisation of influenza A viruses with mutations in segment 5 packaging signals

Influenza A virus vRNA segments contain specific packaging signals at their termini that overlap the coding regions. To further characterise segment 5 packaging signals, we introduced synonymous mutations into the terminal coding regions of the vRNA and characterised the replicative fitness of the r...

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Detalhes bibliográficos
Main Authors: Hutchinson, Edward C., Wise, Helen M., Kudryavtseva, Katerine, Curran, Martin D., Digard, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771075/
https://ncbi.nlm.nih.gov/pubmed/19840659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.05.053
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