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Interfaces and hydrophobic interactions in receptor-ligand systems: A level-set variational implicit solvent approach

A model nanometer-sized hydrophobic receptor-ligand system in aqueous solution is studied by the recently developed level-set variational implicit solvent model (VISM). This approach is compared to all-atom computer simulations. The simulations reveal complex hydration effects within the (concave) r...

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Detalhes bibliográficos
Main Authors: Cheng, Li-Tien, Wang, Zhongming, Setny, Piotr, Dzubiella, Joachim, Li, Bo, McCammon, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Institute of Physics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771049/
https://ncbi.nlm.nih.gov/pubmed/19831428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3242274
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