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The JAK2V617 mutation induces constitutive activation and agonist hypersensitivity in basophils from patients with polycythemia vera

BACKGROUND: The JAK2V617F mutation has been associated with constitutive and enhanced activation of neutrophils, while no information is available concerning other leukocyte subtypes. DESIGN AND METHODS: We evaluated correlations between JAK2V617F mutation and the count of circulating basophils, the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pieri, Lisa, Bogani, Costanza, Guglielmelli, Paola, Zingariello, Maria, Rana, Rosa Alba, Bartalucci, Niccolò, Bosi, Alberto, Vannucchi, Alessandro M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ferrata Storti Foundation 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770964/
https://ncbi.nlm.nih.gov/pubmed/19608683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.007047
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