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Circulating erythrocyte-derived microparticles are associated with coagulation activation in sickle cell disease

BACKGROUND: Sickle cell disease is characterized by a hypercoagulable state as a result of multiple factors, including chronic hemolysis and circulating cell-derived microparticles. There is still no consensus on the cellular origin of such microparticles and the exact mechanism by which they may en...

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Detalhes bibliográficos
Main Authors: van Beers, Eduard J., Schaap, Marianne C.L., Berckmans, René J., Nieuwland, Rienk, Sturk, Augueste, van Doormaal, Frederiek F., Meijers, Joost C.M., Biemond, Bart J.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770961/
https://ncbi.nlm.nih.gov/pubmed/19815831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.008938
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