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Cdc42 Regulates Fc(γ) Receptor-mediated Phagocytosis through the Activation and Phosphorylation of Wiskott-Aldrich Syndrome Protein (WASP) and Neural-WASP

Cdc42 is a key regulator of the actin cytoskeleton and activator of Wiskott-Aldrich syndrome protein (WASP). Although several studies have separately demonstrated the requirement for both Cdc42 and WASP in Fc(γ) receptor (Fc(γ)R)-mediated phagocytosis, their precise roles in the signal cascade leadi...

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Bibliographic Details
Main Authors: Park, Haein, Cox, Dianne
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770938/
https://ncbi.nlm.nih.gov/pubmed/19741094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-03-0230
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