Inhibition of mTOR attenuates store-operated Ca(2+) entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension

Pulmonary vascular remodeling occurs in patients with chronic thromboembolic pulmonary hypertension (CTEPH). One factor contributing to this vascular wall thickening is the proliferation of pulmonary artery smooth muscle cells (PASMC). Store-operated Ca(2+) entry (SOCE) and cytosolic free Ca(2+) con...

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Main Authors: Ogawa, Aiko, Firth, Amy L., Yao, Weijuan, Madani, Michael M., Kerr, Kim M., Auger, William R., Jamieson, Stuart W., Thistlethwaite, Patricia A., Yuan, Jason X.-J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770792/
https://ncbi.nlm.nih.gov/pubmed/19633069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90548.2008
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