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GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A
The SCN5A-encoded cardiac sodium channel underlies excitability in the heart, and dysfunction of sodium current (I(Na)) can cause fatal ventricular arrhythmia in maladies such as long QT syndrome, Brugada syndrome (BrS), and sudden infant death syndrome (SIDS). The gene GPD1L encodes the glycerol ph...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Physiological Society
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770765/ https://ncbi.nlm.nih.gov/pubmed/19666841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00513.2009 |
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