Vaccinia virus decreases major histocompatibility complex (MHC) class II antigen presentation, T-cell priming, and peptide association with MHC class II

Vaccinia virus (VACV) is the current live virus vaccine used to protect humans against smallpox and monkeypox, but its use is contraindicated in several populations because of its virulence. It is therefore important to elucidate the immune evasion mechanisms of VACV. We found that VACV infection of...

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Bibliographic Details
Main Authors: Rehm, Kristina E, Connor, Ramsey F, Jones, Gwendolyn J B, Yimbu, Kenneth, Mannie, Mark D, Roper, Rachel L
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770686/
https://ncbi.nlm.nih.gov/pubmed/20067538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03120.x
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