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BluB cannibalizes flavin to form the lower ligand of vitamin B(12)

Vitamin B(12) (cobalamin) is among the largest known non-polymeric natural products, and the only vitamin synthesized exclusively by microorganisms1. The biosynthesis of the lower ligand of vitamin B(12), 5,6-dimethylbenzimidazole (DMB), is poorly understood1–3. Recently, we discovered that a Sinorh...

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Bibliografiska uppgifter
Huvudupphovsmän: Taga, Michiko E., Larsen, Nicholas A., Howard-Jones, Annaleise R., Walsh, Christopher T., Walker, Graham C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770582/
https://ncbi.nlm.nih.gov/pubmed/17377583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05611
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