Neutralizing antibodies explain the poor clinical response to Interferon beta in a small proportion of patients with Multiple Sclerosis: a retrospective study

BACKGROUND: Neutralizing antibodies (NAbs) against Interferon beta (IFNβ) are reported to be associated with poor clinical response to therapy in multiple sclerosis (MS) patients. We aimed to quantify the contribution of NAbs to the sub-optimal response of IFNβ treatment. METHODS: We studied the pre...

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Main Authors: Sbardella, Emilia, Tomassini, Valentina, Gasperini, Claudio, Bellomi, Francesca, Cefaro, Luca Ausili, Morra, Vincenzo Brescia, Antonelli, Guido, Pozzilli, Carlo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770509/
https://ncbi.nlm.nih.gov/pubmed/19825153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-9-54
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