Population diversity and antibody selective pressure to Plasmodium falciparum MSP1 block2 locus in an African malaria-endemic setting

BACKGROUND: Genetic evidence for diversifying selection identified the Merozoite Surface Protein1 block2 (PfMSP1 block2) as a putative target of protective immunity against Plasmodium falciparum. The locus displays three family types and one recombinant type, each with multiple allelic forms differi...

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Autors principals: Noranate, Nitchakarn, Prugnolle, Franck, Jouin, Hélène, Tall, Adama, Marrama, Laurence, Sokhna, Cheikh, Ekala, Marie-Thérèse, Guillotte, Micheline, Bischoff, Emmanuel, Bouchier, Christiane, Patarapotikul, Jintana, Ohashi, Jun, Trape, Jean-François, Rogier, Christophe, Mercereau-Puijalon, Odile
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770483/
https://ncbi.nlm.nih.gov/pubmed/19832989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-9-219
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