Genome level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome

Human septic shock involves multiple genome-level perturbations. We have conducted microarray analyses in children with septic shock within 24 hours of intensive care unit admission, using whole-blood derived RNA. Based on sequential statistical and expression filters, there were 2,482 differentiall...

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Main Authors: Wong, Hector R., Shanley, Thomas P., Sakthivel, Bhuvaneswari, Cvijanovich, Natalie, Lin, Richard, Allen, Geoffrey L., Thomas, Neal J., Doctor, Allan, Kalyanaraman, Meena, Tofil, Nancy M., Penfil, Scott, Monaco, Marie, Tagavilla, Mary Ann, Odoms, Kelli, Dunsmore, Katherine, Barnes, Michael, Aronow, Bruce J.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770262/
https://ncbi.nlm.nih.gov/pubmed/17374846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00024.2007
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