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Cell-autonomous requirement for DNaseII in non-apoptotic cell death

DNA fragmentation is a critical component of apoptosis but it has not been characterized in non-apoptotic forms of cell death, such as necrosis and autophagic cell death. In mammalian apoptosis, caspase activated DNase (CAD) cleaves DNA into nucleosomal fragments in dying cells, and subsequently DNa...

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Detalhes bibliográficos
Main Authors: Bass, B. Paige, Tanner, Elizabeth A., Martín, Daniel Mateos San, Blute, Todd, Kinser, Ronald D., Dolph, Patrick J., McCall, Kimberly
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770252/
https://ncbi.nlm.nih.gov/pubmed/19557011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.79
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