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INTRARENAL ANGIOTENSIN II IS ASSOCIATED WITH INFLAMMATION, RENAL DAMAGE AND DYSFUNCTION IN DAHL SALT-SENSITIVE HYPERTENSION

BACKGROUND: The goal of this study was to test the hypothesis that intrarenal Ang II has a proinflammatory effect leading to renal damage and dysfunction in Dahl S rats on high Na intake. METHODS: Forty-six 7-to 8-week old Dahl S or R/Rapp strain rats were maintained for 5 weeks on high sodium (8%)...

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Autori principali: Lin, L., Phillips, W. E., Manning, R. D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770181/
https://ncbi.nlm.nih.gov/pubmed/20160914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jash.2009.08.002
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