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17β-Estradiol Protects Against Hypoxic/Ischemic White Matter Damage in the Neonatal Rat Brain

Developing oligodendrocytes (pre-OLs) are highly vulnerable to hypoxic-ischemic injury and associated excitotoxicity and oxidative stress. 17β-Estradiol plays an important role in the development and function of the CNS and is neuroprotective. The sudden drop in circulating estrogen after birth may...

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Main Authors: Gerstner, Bettina, Lee, Joan, DeSilva, Tara M., Jensen, Frances E., Volpe, Joseph J., Rosenberg, Paul A.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770176/
https://ncbi.nlm.nih.gov/pubmed/19224575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22023
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