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The response of the tandem pore potassium channel TASK-3 (K(2P)9.1) to voltage: gating at the cytoplasmic mouth

Although the tandem pore potassium channel TASK-3 is thought to open and shut at its selectivity filter in response to changes of extracellular pH, it is currently unknown whether the channel also shows gating at its inner, cytoplasmic mouth through movements of membrane helices M2 and M4. We used t...

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Autors principals: Ashmole, I, Vavoulis, D V, Stansfeld, P J, Mehta, Puja R, Feng, J F, Sutcliffe, M J, Stanfield, P R
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770146/
https://ncbi.nlm.nih.gov/pubmed/19703964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.175430
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