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Riboswitch Detection Using Profile Hidden Markov Models

BACKGROUND: Riboswitches are a type of noncoding RNA that regulate gene expression by switching from one structural conformation to another on ligand binding. The various classes of riboswitches discovered so far are differentiated by the ligand, which on binding induces a conformational switch. Eve...

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Auteurs principaux: Singh, Payal, Bandyopadhyay, Pradipta, Bhattacharya, Sudha, Krishnamachari, A, Sengupta, Supratim
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770071/
https://ncbi.nlm.nih.gov/pubmed/19814811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-325
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