Ultrafine carbon particles down-regulate CYP1B1 expression in human monocytes

BACKGROUND: Cytochrome P450 monoxygenases play an important role in the defence against inhaled toxic compounds and in metabolizing a wide range of xenobiotics and environmental contaminants. In ambient aerosol the ultrafine particle fraction which penetrates deeply into the lungs is considered to b...

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Main Authors: Eder, Christiane, Frankenberger, Marion, Stanzel, Franz, Seidel, Albrecht, Schramm, Karl-Werner, Ziegler-Heitbrock, Loems, Hofer, Thomas PJ
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770025/
https://ncbi.nlm.nih.gov/pubmed/19835593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-6-27
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