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Tug-of-war between dissimilar teams of microtubule motors regulates transport and fission of endosomes

Intracellular transport is interspersed with frequent reversals in direction due to the presence of opposing kinesin and dynein motors on organelles that are carried as cargo. The cause and the mechanism of reversals are unknown, but are a key to understanding how cargos are delivered in a regulated...

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Main Authors: Soppina, Virupakshi, Rai, Arpan Kumar, Ramaiya, Avin Jayesh, Barak, Pradeep, Mallik, Roop
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770008/
https://ncbi.nlm.nih.gov/pubmed/19864630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906524106
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