Cyclooxygenase-2 Polymorphisms, Aspirin Treatment, and Risk of Colorectal Adenoma Recurrence – Data from a Randomized Clinical Trial

Cyclooxygenase-2 (COX-2) catalyzes the rate-limiting step in the production of prostaglandins, potent mediators of inflammation. Chronic inflammation plays an important role in the development and progression of colorectal cancer. Aspirin inhibits COX-2 activity and lowers the risk of colorectal ade...

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Detalhes bibliográficos
Main Authors: Barry, Elizabeth L., Sansbury, Leah B., Grau, Maria V., Ali, Iqbal U., Tsang, Shirley, Munroe, David J., Ahnen, Dennis J., Sandler, Robert S., Saibil, Fred, Gui, Jiang, Bresalier, Robert S., McKeown-Eyssen, Gail E., Burke, Carol, Baron, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769932/
https://ncbi.nlm.nih.gov/pubmed/19755647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-0363
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