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Overnight Closed-Loop Insulin Delivery with Model Predictive Control: Assessment of Hypoglycemia and Hyperglycemia Risk Using Simulation Studies

BACKGROUND: Hypoglycemia and hyperglycemia during closed-loop insulin delivery based on subcutaneous (SC) glucose sensing may arise due to (1) overdosing and underdosing of insulin by control algorithm and (2) difference between plasma glucose (PG) and sensor glucose, which may be transient (kinetic...

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Autori principali: Wilinska, Malgorzata E., Budiman, Erwin S., Taub, Marc B., Elleri, Daniela, Allen, Janet M., Acerini, Carlo L., Dunger, David B., Hovorka, Roman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Diabetes Technology Society 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769888/
https://ncbi.nlm.nih.gov/pubmed/20144424
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