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Safety and tolerability of bosentan in the management of pulmonary arterial hypertension

Endothelin receptor antagonism has emerged as an important therapeutic approach in pulmonary arterial hypertension (PAH). Bench to bedside scientific research has clearly shown that endothelin-1 (ET-1) is over-expressed in several forms of pulmonary vascular disease and plays an important pathogenet...

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Autors principals: Roberts, Kari E, Preston, Ioana R
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769225/
https://ncbi.nlm.nih.gov/pubmed/19920927
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