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Homodimerization and Heterodimerization of Minimal Zinc(II)-Binding Domain Peptides of T-cell Proteins CD4, CD8α, and Lck
Metal-mediated protein oligomerization is an emerging mode of protein-protein interaction. The C-terminal cytosolic domains of T-cell coreceptors CD4 and CD8α form zinc-bridged heterodimers with the N-terminal region of the kinase Lck, with each protein contributing two cysteinate ligands to the com...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2769085/ https://ncbi.nlm.nih.gov/pubmed/19624124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9028928 |
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