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3-Methylindole is Mutagenic and a Possible Pulmonary Carcinogen
Previous work has shown that bioactivation of the cigarette smoke pneumotoxicant 3-methylindole (3MI) by pulmonary cytochrome P450 enzymes is directly associated with formation of DNA adducts. Here, we present evidence that normal human lung epithelial cells, exposed to low micromolar concentrations...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2769061/ https://ncbi.nlm.nih.gov/pubmed/19700606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp201 |
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