Reduced incidence and severity of experimental autoimmune arthritis in mice expressing catalytically inactive A disintegrin and metalloproteinase 8 (ADAM8)

A disintegrin and metalloproteinase 8 (ADAM8), a catalytically active member of the ADAMs family of enzymes, is expressed primarily on immune cells and thus probably involved in inflammatory responses. ADAM8 is also produced by chondrocytes, and recombinant ADAM8 can induce cartilage catabolism. We...

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Bibliographische Detailangaben
Hauptverfasser: Zack, M D, Melton, M A, Stock, J L, Storer, C E, Barve, R A, Minnerly, J C, Weiss, D J, Stejskal, J A, Tortorella, M D, Turk, J R, Shevlin, K M, Malfait, A-M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2009
Schlagworte:
Animal Studies
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768814/
https://ncbi.nlm.nih.gov/pubmed/19737139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2009.04009.x
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