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Activation and desensitization of the olfactory cAMP-gated transduction channel: identification of functional modules

Olfactory receptor neurons respond to odor stimulation with a receptor potential that results from the successive activation of cyclic AMP (cAMP)-gated, Ca(2+)-permeable channels and Ca(2+)-activated chloride channels. The cAMP-gated channels open at micromolar concentrations of their ligand and are...

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Bibliographic Details
Main Authors: Waldeck, Clemens, Vocke, Kerstin, Ungerer, Nicole, Frings, Stephan, Möhrlen, Frank
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768803/
https://ncbi.nlm.nih.gov/pubmed/19822638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910296
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