Solution structure of S100A1 bound to the CapZ peptide (TRTK12)

As is typical for S100-target protein interactions, a Ca(2+)-dependant conformational change in S100A1 is required to bind to a 12-residue peptide (TRTK12) derived from the actin capping protein, CapZ. In addition, the Ca(2+)-binding affinity of S100A1 is found to be tightened (> 3-fold) when TRT...

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Bibliographische Detailangaben
Hauptverfasser: Wright, Nathan T., Cannon, Brian R., Wilder, Paul T., Morgan, Michael T., Varney, Kristen M., Zimmer, Danna B., Weber, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768541/
https://ncbi.nlm.nih.gov/pubmed/19452629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.01.022
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