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USF functions as a molecular switch during fasting/feeding to regulate lipogenesis. The role of DNA-PK
Lipogenesis is exquisitely regulated by nutritional/hormonal states. Transcription of fatty acid synthase (FAS), a central enzyme in lipogenesis, is low in fasting but increases drastically with feeding. In transcriptional activation of FAS by feeding/insulin, USF constitutively bound to the −65 E-b...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768498/ https://ncbi.nlm.nih.gov/pubmed/19303849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.12.040 |
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