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A New Synthesis and an Antiviral Assessment of the 4'-Fluoro Derivative of 4'-Deoxy-5'-Noraristeromycin

A synthetic route to (1S,2S,3R,5S)-3-(6-amino-9H-purin-9-yl)-5-fluorocyclopentane-1,2-diol (that is, the 4'-fluoro derivative of 4'-deoxy-5'-noraristeromycin, 3) is described via a fluorinated cyclopentanol, which is in contrast to existing schemes where fluorination occurred once the...

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Hlavní autoři: Yin, Xue-qiang, Li, Wei-kuan, Yang, Minmin, Schneller, Stewart W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768480/
https://ncbi.nlm.nih.gov/pubmed/19329326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.03.004
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