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Maternal loading with very low-density lipoproteins stimulates fetal surfactant synthesis

We examined whether administration of very low-density lipoproteins (VLDL) to pregnant rats increases surfactant phosphatidylcholine (PtdCho) content in fetal pre-type II alveolar epithelial cells. VLDL-triglycerides are hydrolyzed to fatty acids by lipoprotein lipase (LPL), an enzyme activated by h...

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Autores principales: Ryan, Alan J., Medh, Jheem D., McCoy, Diann M., Salome, Ronald G., Mallampalli, Rama K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768472/
https://ncbi.nlm.nih.gov/pubmed/12114192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00021.2002
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