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Open-label, clinical phase I studies of tasquinimod in patients with castration-resistant prostate cancer

BACKGROUND: Tasquinimod is a quinoline-3-carboxamide derivative with anti-angiogenic activity. Two open-label phase I clinical trials in patients were conducted to evaluate the safety and tolerability of tasquinimod, with additional pharmacokinetic and efficacy assessments. METHODS: Patients with ca...

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Detalhes bibliográficos
Main Authors: Bratt, O, Häggman, M, Ahlgren, G, Nordle, Ö, Björk, A, Damber, J-E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768463/
https://ncbi.nlm.nih.gov/pubmed/19755981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605322
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