Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis

BACKGROUND: Dysregulation of the cell cycle is a hallmark of many cancers including ovarian cancer, a leading cause of gynaecologic cancer mortality worldwide. METHODS: We examined single nucleotide polymorphisms (SNPs) (n=288) from 39 cell cycle regulation genes, including cyclins, cyclin-dependent...

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Autors principals: Cunningham, J M, Vierkant, R A, Sellers, T A, Phelan, C, Rider, D N, Liebow, M, Schildkraut, J, Berchuck, A, Couch, F J, Wang, X, Fridley, B L, Gentry-Maharaj, A, Menon, U, Hogdall, E, Kjaer, S, Whittemore, A, DiCioccio, R, Song, H, Gayther, S A, Ramus, S J, Pharaoh, P D P, Goode, E L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
Matèries:
Genetics and Genomics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768434/
https://ncbi.nlm.nih.gov/pubmed/19738611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605284
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