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ADENINE NUCLEOTIDE TRANSLOCASE-1 INDUCES CARDIOMYOCYTE DEATH THROUGH UPREGULATION OF THE PRO-APOPTOTIC PROTEIN BAX

Overexpression of the adenine nucleotide translocase (ANT) has been shown to be cytotoxic in several cell types. Although ANT was originally proposed to be a critical component of the mitochondrial permeability transition (MPT) pore, recent data have suggested that this may not be the case. We there...

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Autores principales: Baines, Christopher P., Molkentin, Jeffery D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768428/
https://ncbi.nlm.nih.gov/pubmed/19452617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.01.016
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