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Protein Dynamics in Iron-Starved Mycobacterium Tuberculosis Revealed by Turnover and Abundance Measurement Using Hybrid-Linear Ion Trap-Fourier Transform Mass Spectrometry

To study the proteome response of Mycobacterium tuberculosis H37Rv to a change in iron level, iron-starved late-log-phase cells were diluted in fresh low- and high-iron media containing [(15)N] labeled asparagine as the sole nitrogen source for labeling the proteins synthesized upon dilution. We det...

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Bibliografiske detaljer
Main Authors: Rao, Prahlad K., Rodriguez, G. Marcela, Smith, Issar, Li, Qingbo
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768315/
https://ncbi.nlm.nih.gov/pubmed/18690695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac800288t
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