Validity and Reproducibility of Measurement of Islet Autoreactivity by T-Cell Assays in Subjects With Early Type 1 Diabetes

OBJECTIVE: Type 1 diabetes results from an immunemediated destruction of β-cells, likely to be mediated by T lymphocytes, but the sensitivity, specificity, and other measures of validity of existing assays for islet autoreactive T-cells are not well established. Such assays are vital for monitoring...

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Autori principali: Herold, Kevan C., Brooks-Worrell, Barbara, Palmer, Jerry, Dosch, H. Michael, Peakman, Mark, Gottlieb, Peter, Reijonen, Helena, Arif, Sefina, Spain, Lisa M., Thompson, Clinton, Lachin, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2009
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768166/
https://ncbi.nlm.nih.gov/pubmed/19675135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0249
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