Adipose Tissue Exosome-Like Vesicles Mediate Activation of Macrophage-Induced Insulin Resistance

OBJECTIVE: We sought to determine whether exosome-like vesicles (ELVs) released from adipose tissue play a role in activation of macrophages and subsequent development of insulin resistance in a mouse model. RESEARCH DESIGN AND METHODS: ELVs released from adipose tissue were purified by sucrose grad...

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Hauptverfasser: Deng, Zhong-bin, Poliakov, Anton, Hardy, Robert W., Clements, Ronald, Liu, Cunren, Liu, Yuelong, Wang, Jianhua, Xiang, Xiaoyu, Zhang, Shuangqin, Zhuang, Xiaoying, Shah, Spandan V., Sun, Dongmei, Michalek, Sue, Grizzle, William E., Garvey, Timothy, Mobley, Jim, Zhang, Huang-Ge
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2009
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768161/
https://ncbi.nlm.nih.gov/pubmed/19675137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0216
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