Otitis media in a mouse model for Down syndrome

The Ts65Dn mouse shares many phenotypic characteristics of human Down syndrome. Here, we report that otitis media, characterized by effusion in the middle ear and hearing loss, was prevalent in Ts65Dn mice. Of the 53 Ts65Dn mice tested, 81.1% had high auditory-evoked brainstem response (ABR) thresho...

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Bibliografiske detaljer
Main Authors: Han, Fengchan, Yu, Heping, Zhang, Jiangping, Tian, Cong, Schmidt, Cecilia, Nava, Casey, Davisson, Muriel T, Zheng, Qing Y
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2009
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768146/
https://ncbi.nlm.nih.gov/pubmed/19765102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2009.00677.x
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