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A Novel Approach for Efficient Pharmacophore-based Virtual Screening: Method and Applications

Virtual screening is emerging as a productive and cost-effective technology in rational drug design for the identification of novel lead compounds. An important model for virtual screening is the pharmacophore. Pharmacophore is the spatial configuration of essential features that enable a ligand mol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dror, Oranit, Schneidman-Duhovny, Dina, Inbar, Yuval, Nussinov, Ruth, Wolfson, Haim J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767445/
https://ncbi.nlm.nih.gov/pubmed/19803502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci900263d
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