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Hedgehog pathway responsiveness correlates with the presence of primary cilia on prostate stromal cells

BACKGROUND: Hedgehog (Hh) signaling from the urogenital sinus (UGS) epithelium to the surrounding mesenchyme plays a critical role in regulating ductal formation and growth during prostate development. The primary cilium, a feature of most interphase vertebrate cell types, serves as a required local...

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Autori principali: Zhang, Jingxian, Lipinski, Robert J, Gipp, Jerry J, Shaw, Aubie K, Bushman, Wade
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767347/
https://ncbi.nlm.nih.gov/pubmed/19811645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-9-50
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