Clone clusters in autoreactive CD4 T-cell lines from probable multiple sclerosis patients form disease-characteristic signatures

We developed a method for selectively propagating disease-related autoreactive T-cell lines (auTCLs) based on their increased resistance to apoptosis. The generated auTCLs homogeneously co-express CD45RO and CD49a, adhere strongly to extracellular matrix proteins and express high interleukin-17 (IL-...

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Autors principals: Mandel, Mathilda, Achiron, Anat, Tuller, Tamir, Barliya, Tilda, Rechavi, Gideon, Amariglio, Ninette, Loewenthal, Ron, Lavie, Gad
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2009
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767318/
https://ncbi.nlm.nih.gov/pubmed/19740385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03117.x
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