Permeation of topically applied caffeine through human skin – a comparison of in vivo and in vitro data

AIMS: Due to ethical reasons, in vivo penetration studies are not applicable at all stages of development of new substances. Therefore, the development of appropriate in vitro methods is essential, as well as the comparison of the obtained in vivo and in vitro data, in order to identify their transf...

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Detalhes bibliográficos
Main Authors: Trauer, Sindy, Patzelt, Alexa, Otberg, Nina, Knorr, Fanny, Rozycki, Christel, Balizs, Gabor, Büttemeyer, Rolf, Linscheid, Michael, Liebsch, Manfred, Lademann, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767280/
https://ncbi.nlm.nih.gov/pubmed/19694736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03463.x
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