Permeation of topically applied caffeine through human skin – a comparison of in vivo and in vitro data

AIMS: Due to ethical reasons, in vivo penetration studies are not applicable at all stages of development of new substances. Therefore, the development of appropriate in vitro methods is essential, as well as the comparison of the obtained in vivo and in vitro data, in order to identify their transf...

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Bibliografiske detaljer
Main Authors: Trauer, Sindy, Patzelt, Alexa, Otberg, Nina, Knorr, Fanny, Rozycki, Christel, Balizs, Gabor, Büttemeyer, Rolf, Linscheid, Michael, Liebsch, Manfred, Lademann, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2009
Fag:
Pharmacokinetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767280/
https://ncbi.nlm.nih.gov/pubmed/19694736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03463.x
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