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Prediction of Protein-Protein Interfaces on G-Protein β Subunits Reveals a Novel Phospholipase C β2 Binding Domain

Gβ subunits from heterotrimeric G-proteins directly bind diverse proteins, including effectors and regulators, to modulate a wide array of signaling cascades. These numerous interactions constrained the evolution of the molecular surface of Gβ. Though mammals contain five Gβ genes comprising two cla...

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Bibliografski detalji
Glavni autori: Friedman, Erin J., Temple, Brenda R. S., Hicks, Stephanie N., Sondek, John, Jones, Corbin D., Jones, Alan M.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767172/
https://ncbi.nlm.nih.gov/pubmed/19646992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.076
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