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Molecular Basis of Complete Complement C4 Deficiency in Two North-African Families with Systemic Lupus Erythematosus (SLE)
Complete deficiency of complement C4 is among the strongest genetic risk factors for human SLE. C4 is a constituent of the RP-C4-CYP21-TNX (RCCX) module in the HLA that exhibits inter-individual copy-number and gene-size variations. Here we studied two North-African families with complete C4 deficie...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2767122/ https://ncbi.nlm.nih.gov/pubmed/19279649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2009.10 |
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