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DNA Damage/Repair and Polymorphism of the hOGG1 Gene in Lymphocytes of AMD Patients

Oxidative stress is thought to play a role in the pathogenesis of age-related macular degeneration (AMD). We determined the extent of oxidative DNA damage and the kinetics of its removal as well as the genotypes of the Ser326Cys polymorphism of the hOGG1 gene in lymphocytes of 30 wet AMD patients an...

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Hlavní autoři: Wozniak, Katarzyna, Szaflik, Jacek P., Zaras, Malgorzata, Sklodowska, Anna, Janik-Papis, Katarzyna, Poplawski, Tomasz R., Blasiak, Janusz, Szaflik, Jerzy
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766933/
https://ncbi.nlm.nih.gov/pubmed/19885394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/827562
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